About this product

Name: 2-Fluorodeschloroketamine  Cas: 111982-50-4

Other names: 2-FDCK, 2′-Fl-2-Oxo-PCM, Fluoroketamine2-(2-fluorophenyl)-2-(methylamino)cyclohexan-1-one)

2-Fluorodeschloroketamine (2-FDCK) as a substitute for ketamine has emerged among drug abusers in recent years. However, 2-FDCK has not been controlled or regulated in many countries, which may be partly related to the lack of evidence on its abuse potential. In this study, we evaluated the abuse potential of 2-FDCK via the tests of conditioned place preference (CPP), locomotor sensitization, drug self-administration, and drug discrimination using ketamine as a reference. 2-FDCK induced significant CPP at a minimum dose of 3 mg/kg in mice, an effect comparable to that of ketamine (3 mg/kg).